Gene

lmod1b

ID
ZDB-GENE-141215-22
Name
leiomodin 1b (smooth muscle)
Symbol
lmod1b Nomenclature History
Previous Names
  • si:ch211-137o16.10
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have actin binding activity and tropomyosin binding activity. Predicted to be involved in muscle contraction and pointed-end actin filament capping. Human ortholog(s) of this gene implicated in megacystis-microcolon-intestinal hypoperistalsis syndrome. Orthologous to human LMOD1 (leiomodin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Whitesell et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa35083Allele with one point mutationUnknownPremature StopENU
1 - 1 of 1
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Sequence Targeting Reagents
No data available
Human Disease
Associated With lmod1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Megacystis-microcolon-intestinal hypoperistalsis syndrome 3 619362
1 - 1 of 1
Associated With lmod1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003124 WH2 domain
Family IPR004934 Tropomodulin
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
1 - 3 of 3
Domain Details Per Protein
Protein Length Leucine-rich repeat domain superfamily Tropomodulin WH2 domain
UniProtKB:A0A8M1Q744 671
UniProtKB:E7F062 671
1 - 2 of 2
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 11
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lmod1b-201 (1) Ensembl 2,715 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-137O16ZFIN Curated Data
1 - 1 of 1
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanLMOD11
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseLmod11
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations